The IRS of all places, has a convenient page that gives a quick list of "Real Estate Tax Tips."  Have a look at his here.

Some of the tips include:

-"If you have a gain from the sale of your main home, you may be able to exclude up to $250,000 of the gain from your income."

-"You cannot deduct a loss from the sale of your main home."

There obviously quite a few more and they are surprisingly easy to follow.  Perhaps if you qualify for one, you probaby didn't even know it!

If you do qualify, and save some cash, do yourself a favor, and treat yourself to something!